| Title: | Proton magnetic resonance spectroscopy in oncology: the fingerprints of cancer? |
| Authors: | Roberto García-Figueiras, Sandra Baleato-González, Anwar R Padhani, Laura Oleaga, Joan C Vilanova, Antonio Luna, Juan Carlos Cobas Gómez |
| Date: | 2016/09/13 |
| Reference: | Diagn Interv Radiol 2016; 22: 75-89 |
| DOI: | http://dx.doi.org/10.5152/dir.2015.15009 |
| Download link: | http://www.dirjournal.org/eng/makale/1415/80/Full-Text |
ABSTRACT
Abnormal metabolism is a key tumor hallmark. Proton magnetic resonance spectroscopy (1H-MRS) allows measurement of metabolite concentration that can be utilized to characterize tumor metabolic changes. 1H-MRS measurements of specific metabolites have been implemented in the clinic. This article performs a systematic review of image acquisition and interpretation of 1H-MRS for cancer evaluation, evaluates its strengths and limitations, and correlates metabolite peaks at 1H-MRS with diagnostic and prognostic parameters of cancer in different tumor types.
